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內容簡介: 博客來網路書局Mega Goal is a dynamic American English series for international communication designed for teenagers and young adults that takes students from absolute beginners to high-intermediate level. The Intro level and Books 1-6 integrate the four skills, present the grammar in context, and help students develop natural conversation. With eye-catching art and high-interest topics, Mega Goal is easy and enjoyable to teach and to learn from.

Features:* Unit openers, enhanced by attractive and contemporary illustrations, help students make visual connections and retain博客來網路書店 the new language.

* Units are thematic and contain high-interest topics that relate to students' age and interests.

* A consistent unit format博客來 makes navigation clear and predictable.

* The Grammar section offers succinct explanations, followed by activities that reinforce the grammar points presented.

* Interactive Conversations allow students to choose or make up their own endings.

* Vocabulary development occurs throughout and everyday expressions are explained in the Real Talk feature.

* Sections on Pronunciation, Listening, and Writing are included in each unit.

* Readings and Projects at the end of each unit allow students to experience real world situations.

* Commercial-quality songs enable students to expand their language in a pleasant way.

* Learning strategies and critical thinking skills prepare students for success.博客來書店* Humor and cross-cultural information and values are present throughout the series.

• 已追蹤作者：[ 修改 ]

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  作者： Manuel Dos Santos    新功能介紹
• 出版社：東華    新功能介紹
• 出版日期：2010/05/19
• 語言：英文

Mega Goal (2) Workbook購物網

內容來自YAHOO新聞

華人攜YAP1基因異常 罹肺腺癌高5.9倍

中國時報【林宜慧╱台北報導】

肺癌高居癌症死亡率首位，台灣每年新增1萬2000名患者，且有9000名致死，然而肺癌初期無明顯症狀且易復發，常在發現時為時已晚。台大校長楊泮池領導跨校研究團隊費時逾3年，發現華人若攜帶YAP1基因異常者，肺腺癌風險是其他人的5.9倍，未來可藉此篩檢出高風險族群，並及早診斷、治療。

未抽菸罹肺癌？解謎

這項研究由台大、中研院、台中榮總等單位共同完成。楊泮池指出，肺癌分類中以不吸菸族群的肺腺癌為大宗，男性占60％、女性則高占70％。團隊首先找出一個高度發生肺癌的家族，罹肺癌的媽媽生下5位子女中，4女未抽菸罹患肺腺癌，1兒子菸酒都沾，但無發病；進行全基因體組高速定序分析後，找出與肺腺癌的相關基因異常。

接著，團隊再利用1千多名肺腺癌病人對照1千多名健康人，發現基因YAP1上1個定位點異常與肺腺癌有關，其中13名攜帶YAP1基因的親屬中，就高達10名罹患肺腺癌或有發現癌前病變，攜帶此異常基因者風險是未攜帶者的5.9倍。

楊泮池表示，肺癌風險有家族聚集傾向，直系血親的家族史肺癌風險高很多，但目前無法斷定主因是基因或相同環境暴露影響，研究發現YAP1基因異常攜帶率低，為0.18％，換算全台約4萬餘人，但攜帶者發病率高。

攜帶者發病低於60歲

此外，肺癌好發年齡男性為60-65歲，女性是55-60歲，但攜帶YAP1基因異常的好發年齡相對年輕，研究中23名肺腺癌病人，就有12名發病年齡小於60歲，也顯示攜帶YAP1基因異常有早發性肺腺癌的可能。

及早篩檢95％可痊癒

楊泮池表示，研究出YAP1基因異常有高肺腺癌風險，未來即可針對攜帶此異常基因者進行低劑量斷層掃描，以早期篩檢出肺腺癌，若在腫瘤1公分內就手術切除，95％病人可痊癒，不須後續的化療、標靶治療；但因為種族各異，此項研究成果僅限於華人。

中央研究院統計科學研究所助研究員陳宇表示，此篩檢方式目前尚未開放一般民眾，預計1-3年後醫院可供民眾檢測。

新聞來源https://tw.news.yahoo.com/華人攜yap1基因異常-罹肺腺癌高5-9倍-215008071.html

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